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Angela Stoeckman

Job Title

  • Associate Professor of Chemistry
    Chemistry, College of Arts and Sciences

Highlight

I am interested in the regulation of fatty acid metabolism. Fatty acids are not only important in the generation of ATP/energy, but they are important signaling molecules and inflammatory mediators. Fatty acids are stored as triacylglycerol (TAG) molecules in a dynamic cellular organelle called the lipid droplet. My research focuses on proteins that coat these lipid droplets in the hepatocyte and act to regulate the entry or exit of TAGs.

Started at Bethel

2015

Education

  • Bethel University - B.S., 1997
  • University of Minnesota - Ph.D., 2003

Publications

van de Veerdonk, F. L., Stoeckman, A. K., Wu, G., Boeckermann, A. N., Azam, T., Netea, M. G., Joosten, L. A., van der Meer, J. W., Hao, R., Kalabokis, V., and Dinarello, C. A. (2012). IL-38 Binds to the IL-36 Receptor and has Biological Effects on Immune Cells Similar to IL-36 Receptor Antagonist. PNAS. 109, 3001-3005.

Stoeckman, A. K., Baechler, E. C., Ortmann, W. A., Behrens, T. W., Michet, C. J., Peterson, E. J. (2006). A Distinct Inflammatory Gene Expression Profile In Patients With Psoriatic Arthritis. Genes and Immunity. 7, 583-591.

Stoeckman, A. K., Ma, L., and Towle, H. C. (2004). Mlx is the Functional Heteromeric Partner of ChREBP in Glucose Regulation of Lipogenic Enzyme Genes. J. Biol. Chem. 279, 15662-15669.

Wu, C., Okar, D. A., Stoeckman, A. K., Peng, L.-J., Herrera, A. H., Herrera, J. E., Towle, H. C., and Lange, A. J. (2004). A Potential Role for Fructose-2,6-Bisphosphate in the Stimulation of Hepatic Glucokinase Gene Expression. Endocrinology 145, 650-658.

Stoeckman, A. K. and Towle, H. C. (2002). The Role of SREBP-1c in Nutritional Regulation of Lipogenic Enzyme Gene Expression. J. Biol. Chem. 277, 27029-27035.

Koo, S.-H., Dutcher, A. K., and Towle, H. C. (2001). Glucose and Insulin Function through Two Distinct Transcription Factors to Stimulate Expression of Lipogenic Enzyme Genes in Liver. J. Biol. Chem. 276, 9437-9445.

Davey, G. M., Schober, S. L., Endrizzi, B. T., Dutcher, A. K., Jameson, S. C., Hogquist, K. A. (1998). Preselection Thymocytes Are More Sensitive to T Cell Receptor Stimulation Than Mature T Cells. J. Exp. Med. 188, 1867-1874.

Presentations

Presented Research Poster at the August 2005 “Immunochemistry and Immunobiology” Gordon Conference held at Queen’s College in Oxford, England. “The Role of a Variant Lymphoid Phosphatase in T Cell Development and Function.”

Presented Research Poster at The Endocrine Society’s 84th annual meeting (June 2002) San Francisco, CA. “The Role of SREBP-1c in Nutritional Regulation of Lipogenic Enzyme Gene Expression.”

Presented Research Poster at the 1999 ASBMB Fall Symposium “Nutritional Control of Gene Transcription” held in Taos, New Mexico. “Regulation of Uncoupling Protein-2 in the Hepatocyte by Polyunsaturated Fatty Acids.”

Research interests

I am interested in the regulation of fatty acid metabolism. Fatty acids are not only important in the generation of ATP/energy, but they are important signaling molecules and inflammatory mediators. Fatty acids are stored as triacylglycerol (TAG) molecules in a dynamic cellular organelle called the lipid droplet. My research focuses on proteins that coat these lipid droplets in the hepatocyte and act to regulate the entry or exit of TAGs.